Winslow Professor of Chemistry George Shields presented a seminar, "Computational Design and Experimental Discovery of an Anti-estrogenic Peptide Derived from Alpha-Fetoprotein," to an audience of 60 faculty and students in the department of chemistry and biochemistry at Middlebury College on March 16. His lecture highlighted the work that he and Karl Kirschner, co-director of the Center for Molecular Design, have carried out with Hamilton students over the past few years.
Shields discussed the work of Katrina Lexa '05, Katherine Alser '09, Amanda Salisburg '05, Damien Ellens '03, Lorena Hernandez '03, Sam Bono '00, Jennifer Derby '01, and Jaime Skiba '02 in detail. In addition he talked about the research that Karilyn Larkin '06, Amy Barrows '08, Alexa Schwarzman '09, Sarah Taylor '03, Abby Markeson '04, Valery Danilack '06, and Sarah Felder '07 have done on developing a computational assay for the Estrogen Receptor. Shields also talked about the group's work on enediyne anticancer antibiotics, especially the work of Frank Pickard '05, Chantelle Rein '03, Becky Shepherd '06, and Amber Gillis '06.
