Associate Professor of Chemistry Adam Van Wynsberghe presented an invited seminar titled “Development of a multi-scale sampling methodology to examine the favored ligand binding pathways of influenza neuraminidase” at Union College on May 12. His presentation was part of Union’s Department of Chemistry Seminar Series.
Van Wynsberghe detailed the work his laboratory has accomplished over the last few years in investigating how small molecules bind to the major drug target of influenza, the neuraminidase protein.
His primary focus was on the work of Pat Marris ’16, Leah Krause ’14 and Alvin Wu ’13. Other early contributors also included Dan Mermelstein ’14, Jeremy Adelman ’13 and Rebecca Green ’11.
The Van Wynsberghe research group uses computational and theoretical techniques to study protein-ligand binding and the functional implications of protein dynamics. The group’s general goals are to use chemical and physical principles to understand interesting problems in biochemistry and biophysics.