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Re-engineering the Gut Microbiota Towards Improved Brain Health with Katie Guzzetta ’18

4/17/2023, 12:00 PMVIRTUAL

Trillions of microorganisms live on and within your body, where they contribute to your digestion, immunity, neurodevelopment and overall health. Unlike animalian genetics, the gut microbiome is highly accessible to modification within a living organism, including via antibiotics, diet, and other environmental factors, putting it on the frontier of modern medicine. Join HCN and Katie Guzzetta ’18 who will highlight recent research in the field of the microbiota-gut-brain axis, discuss how the gut microbiota contributes to behavior, health, and disease, and provide an outlook on emerging gut microbiome-based diagnostics and therapeutics for mammalian health.

After majoring in Biochemistry & Molecular Biology at Hamilton College, Dr. Katie Guzzetta ’18 pursued her PhD in Anatomy & Neuroscience with Prof. John Cryan and Dr. Olivia O'Leary at APC Microbiome Ireland, University College Cork, where she studied how the trillions of microorganisms which reside within the gut impact brain health following stress and during aging. Her main findings were that transferring gut microbiota from young mice into old mice could rejuvenate their learning and memory. Following her PhD, Katie completed a short sabbatical at Harvard Medical School in the lab of Dr. Laurie Cox, supporting research investigating the causative and potentially therapeutic role of specific gut bacteria in Alzheimer's Disease. Currently, Katie works as a postdoctoral researcher with Prof. Randall Platt at ETH Zurich in Basel, Switzerland, where she is harnessing CRISPR technology to reengineer these microbes to noninvasively diagnose diseases from within the intestines through a transcriptional recording technique called Record-Seq.

Cost to register for your first event is $10, which goes directly to funding and expanding the virtual programming series, while a portion is contributed to the Hamilton Fund to support teaching and learning on College Hill. 

Did you know you know you can become a Virtual Event Pass (VEP) holder? After you have paid the one-time $10 registration for the first event you attend, you can then register to attend all subsequent virtual events for free until June 30, 2023! Pay once. Attend unlimited. With the Virtual Event Pass you’re supporting Hamilton and staying connected to your Hamily. It’s a win-win!

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